Scientist/Research Scientist, Molecular Pharmacology (contract position) Job at Septerna, South San Francisco, CA

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  • Septerna
  • South San Francisco, CA

Job Description

Septerna seeks a contract molecular pharmacologist to develop quantitative biochemical assays supporting GPCR drug discovery. The role involves hands-on assay development and optimization using luminescence and fluorescence platforms applied to their Native Complex Platform.

Responsibilities

  • Develop and optimize plate-based displacement binding assays supporting drug discovery projects
  • Collaborate with discovery biology colleagues to prioritize and advance assay science
  • Perform hands-on experimental work with purified proteins and cellular preparations
  • Maintain laboratory documentation and conduct data analysis

Requirements

  • BS with 10+ years hands-on in vitro pharmacology experience, or PhD in pharmacology/biochemistry/biophysics
  • Demonstrated experience with NanoBRET, NanoBiT, BRET, TR-FRET, or fluorescence polarization assays
  • Proficiency in assay development for GPCRs or membrane protein systems
  • Strong laboratory documentation and data analysis skills
  • Ability to work collaboratively within multidisciplinary drug discovery teams

Job Tags

Contract work

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